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Mentally engaging activities, such as playing a video game, solitaire, chess, doing a crossword puzzle, or even having a mentally stimulating conversation can markedly reduce or eliminate RLS symptoms when the patient is sedentary, which is based on hundreds of anecdotal reports to the author and other RLS experts

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Schmidt SF, Rohm M, Herzig S, Berriel Diaz M

Acta Neuropathol 120:755764

However, one study of severely underweight women with anorexia found that carnitine supplements did not raise levels of this amino acid in the blood nor did it improve muscle weakness